Analgesics and Anti-pyre tics

1. Salicylates

Acetyl-salicylic acid

Sodium salicylate

Methyl salycilate

Salicylic acid

2.Para- aminophenol derivatives

Paracetamol

Phenacetin

3. Pyrazolon derivatives

Phenyl butazone

Oxypehenbutazone

Aminopyrine

Antipyrine

 4. Propionic acid derivatives

Ibuprofen

Ketoprofen

5. Miscellaneous

Indomethacin

Diclofenac sodium

Nimesulide

Mefenamic acid

Metamizole

Opioid analgesics

1. According to ring structure

A . Phenanthrene derivatives

Morphine

Codeine

Thebaine

B . Benzo-isoquinoline derivatives

Papaverine

Noscapine

11. According to synthesis

A. Natural opium alkaloids

Morphine

Codeine

B. Semi synthetic opium alkaloids

Heroine

Pholcodeine

C. Synthetic opiods

Pethidine

Methadine

Tramadol

Hypnotics and sedatives

Hypnotics are drugs which produce sleep resembling natural sleep

Sedatives are drugs which reduce excitement without producing sleep

                                                                                                      

1. Barbiturate derivatives
2. Non – barbiturate derivatives

 

1 .Barbiturate derivatives

A. Long acting barbiturates   (8 -12 hours )

 Phenobarbitone

 Mephobarbitone

 Methylphenobarbitone

 Barbitone

B. Intermediate acting barbiturates

Amylobarbitone

Butobarbitone

Allobarbitone

Vinbarbitone

 C. Short acting barbiturates

 Pentobarbitone

Secobarbitone

Cyclobarbitone

Hepatobarbitone

  

D. Ultra short acting barbiturates

 Thiobarbitone

Hexabarbitone

Methobarbitone

2. Non –barbiturate derivatives

A. Benzodiazepines

Diazepam

Oxazepam

B. Chloral derivatives

Chloral hydrate

Chloral formamide

Butyl chloral hydrate

C. Aldehydes

Paraldehyde

D. Bromides

Potassium bromide

Sodium bromide

Ammonium bromide

E. Alcohols

Ethyl alcohol

Tribromoehamol

Amylene hydrate

F. Piperidine derivatives

Glutethimide

Methyprylon

Ganglionic blocking agents

1. Selective blocking agents

Nicotine

Lobeline

Dimethyl phenyl piperazinium iodide (DMPP)

Tetra methyl ammonium (TMA)

2. Non selective  muscarinic agonists

Acetylcholine

Carbachol

Pilocarpine

Anticholinesterases

Ganglionic Blocking Agents

These drugs inhibit the passage of nerve impulse from preganglionic neurons to postganglionic neurons

 Classification depend upon of the mode of action

1. Competitive blockers

A. Quaternary ammonium compounds

Hexamethonium

Pentolinium

B. Amines

Mecamylamine

Pempidine

C. Monosulfonium compound

Trimethaphan camforsulfonate

11. Non competitive agents

Nicotine

Procaine

Hemicholinium