Pharmacology ( rang & dale )

This highly acclaimed textbook is a worldwide bestseller, recognized for its emphasis on the mechanisms by which drugs act at the cellular and molecular levels and how that relates to their overall pharmacological effects and clinical uses. The 5th Edition includes four new chapters, a reorganized and expanded section on treatments for infections and cancer, and thorough updates throughout that explore new treatments and advances in molecular biology that may lead to future therapeutic options for cancer, HIV infection, osteoporosis, neurodegenerative disorders, erectile dysfunction, obesity, diabetes, atherosclerosis, cardiac failure, and more. User-friendly features include new chapter overviews reviews of relevant physiology and biochemistry boxed key points and clinical uses references and reading lists a new full-color art program and new "small print" sections that separate the more complex material from the main discussion thread in each chapter, leaving the depth of coverage to the reader's discretion.

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cGMP: Generators, Effectors and Therapeutic Implications

After the discovery of endogenous NO formation in the late '80s and the 1998 Nobel Prize in Physiology or Medicine, many researchers and physicians again became interested in the NO/sGC interaction and cGMP-dependent signaling. This book is an enthusiastic celebration of cyclic guanosine monophosphate (cGMP) and amply illustrates the importance of this field of science to patients and the way in which the field has evolved. It is exclusively devoted to this exciting and important signaling molecule, addressing all recent advances in understanding guanylate cyclase regulation, NO/sGC interactions, cGMP effector mechanisms and their pathophysiological and pharmacological implications. Particular attention will also be given to clinical applications of the novel cGMP-elevating drugs which are on the horizon, thus spanning the continuum from basic science to clinic.

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Encyclopedia of Molecular Pharmacology, 2nd edition

An essential text, this is a fully updated second edition of a classic, now in two volumes. It provides rapid access to information on molecular pharmacology for research scientists, clinicians and advanced students. With the A-Z format of over 2,000 entries, around 350 authors provide a complete reference to the area of molecular pharmacology. The book combines the knowledge of classic pharmacology with the more recent approach of the precise analysis of the molecular mechanisms by which drugs exert their effects. Short keyword entries define common acronyms, terms and phrases. In addition, detailed essays provide in-depth information on drugs, cellular processes, molecular targets, techniques, molecular mechanisms, and general principles.

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Safety Pharmacology In Pharmaceutical Development And Approval

Safety Pharmacology In Pharmaceutical Development And Approval

Providing detailed coverage of an emerging discipline within the pharmaceutical industry, Safety Pharmacology in Pharmaceutical Development and Approval lays out exactly the whys and hows of safety pharmacology testing. The book covers the background, history, and concerns that have evolved from lackluster safety pharmacology activities in the past. It details regulatory requirements, provides comprehensive information on study designs, and covers both the required battery of studies and the supplemental, follow-up battery. The author addresses how best to implement ICH safety standards and how to integrate pharmacology safety evaluations into existing safety evaluations.

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Pharmacology: Principles and Practice

Pharmacology: Principles and Practice Summary:

By Miles Hacker, William S. Messer II, Kenneth A. Bachmann

• Publisher: Academic Press
• Number Of Pages: 640
• Publication Date: 2009-09-14
• ISBN-10 / ASIN: 012369521X
• ISBN-13 / EAN: 9780123695215

This unique and much needed textbook meets the rapidly emerging needs of programs training pharmacologic scientists seeking careers in basic research and drug discovery rather than such applied fields as pharmacy and medicine. While the market is crowded with many clinical and therapeutic pharmacology textbooks, the field of pharmacology is booming with the prospects of discovering new drugs, and virtually no extant textbook meets this need at the student level. The market is so bereft of such approaches that many pharmaceutical companies will adopt Hacker, et al. to help train new drug researchers.

The boom in pharmacology is driven by the recent decryption of the human genome and enormous progress in controlling genes and synthesizing proteins, making new and even custom drug design possible. This book makes use of these discoveries in presenting its topics, moving logically from drug receptors to the target molecules drug researchers seek, covering such modern topics along the way as side effects, drug resistance, Pharmacogenomics, and even nutriceuticals, one in a string of culminating chapters on the drug discovery process.

*Uses individual drugs to explain molecular actions

*Full color art program explains molecular and chemical concepts graphically

*Logical structure reflecting the current state of pharmacology and translational research, starting with receptors and finishing with target molecules

*Covers such intricacies as drug resistance and cell death

*Consistent format across chapters and pedagogical strategies make this textbook a superior learning tool

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Manual of Psychiatric Therapeutics

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British Pharmacopoeia (£818.19 Value!)

British Pharmacopoeia (£818.19 Value!)

Publisher: Stationery Office | ISBN 10 0113227256 | ISO | 394.3MB

The British Pharmacopoeia (BP) is the authoritative, current collection of standards for UK medicinal substances and the official source of all UK quality standards. It is an essential reference for anyone involved in pharmaceutical Research and Development, manufacturing and testing, and plays a vital role in ensuring that all medicinal substances on the UK market meet standards of safety, quality and efficacy.

The BP is supplied in a variety of formats designed for ease of use and a wide range of applications. The hard copy edition package contains a boxed five volume set with a separate Veterinary volume, a CD-ROM and access to a comprehensible, regularly updated website. Both the CD-ROM and online formats are easy to network for access across your organisation.

Key features

* Extensive Revisions including 30 new BP texts
* New Supplementary Chapters containing general guidance on Unlicensed Medicines and Method Validation
* First BP monograph for Traditional Chinese Medicines
* European Pharmacopoeia (Ph Eur) monographs up to and including Ph Eur 5th edition Supplement 5.5
* The CD-ROM and online version of the BP can be made available to multiple users through a network licence, which is more economical than purchasing multiple copies of the BP package
* Technical support for network licence holders is available from TSO, the publisher of the BP
* CD-ROM and website deliver the complete text of the British Pharmacopoeia, British Approved Names and European Pharmacopoeia standards directly to your PC

Extent 3500 pages

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