Antimicrobial Susceptibility Testing Protocols

Monday, September 6, 2010



The reported increase in the occurrence of antibiotic-resistant bacteria serves to emphasize the importance of accurate susceptibility testing. This timely guide examines the role of the clinical microbiology lab in integrated patient care. The first section addresses basic susceptibility disciplines such as macro and microbroth dilution, agar dilution, and disk diffusion. The second section considers specialized susceptibility protocols that may be performed by a subset of labs, and emphasizes reproducible results. The third section covers antibiotic development and discusses antibiogram design and use. It includes extensive references and a table of antibiotic classes and common bug-drug susceptibilities.

 

Basic & Clinical Pharmacology



The current science of pharmacology-and its clinical applications-at your fingertips
Now in its 25th year of publication, Basic and Clinical Pharmacology is the most up-to-date and complete pharmacology textbook available. Through nine previous editions it has set the standard for concise and easy-to-read, yet comprehensive coverage of pharmacology. The text's integration of basic with clinical science makes it well suited for an integrated organ-system-based curricula as well as the more traditional curricula.
Features

  • In-depth coverage of key pharmacology topics, from basic principles to pharmacologic considerations for autonomic, cardiovascular-renal, smooth muscle, CNS, endocrine, antimicrobial, and chemotherapeutic and immunotherapeutic drugs

  • Updated with dozens of new, recently approved drugs, including monoclonal antibodies

  • Detailed review of the mechanism of action and toxicities of traditional and newer drugs

  • Critical discussions of treatment strategies and recommended drugs for all major diseases

  • Valuable section on toxicology that provides an introduction to occupational and environmental toxicology; heavy metal intoxication and chelators; and management of the poisoned patient

  • Ready-to-use, study-enhancing features, including special interest boxes, lists of common preparations, and dosage information

  • Unique evidence-based chapters on abused drugs; special aspects of perinatal, pediatric, and geriatric pharmacology; and over-the-counter drugs, herbal medications, and nutritional supplements

  • More than 500 concept-clarifying illustrations and tables throughout


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    Pharmacotherapy Handbook



    The second edition of the Pharmacotherapy Handbook provides readers with a portable, readable guide that is integral to any clinical setting. Bold-face type highlights drug names when they first appear and in all closing information. The book's bulleted format helps readers find the information they need immediately. This updated book was designed as a companion text for the fourth edition Pharmacotherapy: A Pathophysiologic Approach.


     
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    Goodman & Gilman's The Pharmacological Basis of Therapeutics


    The undisputed leader in medical pharmacology, without equal. Updated to reflect all critical new developments in drug action and drug-disease interaction. This is the “desert island” book of all medical pharmacology—if you can own just one pharmacology book, this is it.


     
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    Pharmacology ( rang & dale )





    This highly acclaimed textbook is a worldwide bestseller, recognized for its emphasis on the mechanisms by which drugs act at the cellular and molecular levels and how that relates to their overall pharmacological effects and clinical uses. The 5th Edition includes four new chapters, a reorganized and expanded section on treatments for infections and cancer, and thorough updates throughout that explore new treatments and advances in molecular biology that may lead to future therapeutic options for cancer, HIV infection, osteoporosis, neurodegenerative disorders, erectile dysfunction, obesity, diabetes, atherosclerosis, cardiac failure, and more. User-friendly features include new chapter overviews reviews of relevant physiology and biochemistry boxed key points and clinical uses references and reading lists a new full-color art program and new "small print" sections that separate the more complex material from the main discussion thread in each chapter, leaving the depth of coverage to the reader's discretion.


     
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    cGMP: Generators, Effectors and Therapeutic Implications



    After the discovery of endogenous NO formation in the late '80s and the 1998 Nobel Prize in Physiology or Medicine, many researchers and physicians again became interested in the NO/sGC interaction and cGMP-dependent signaling. This book is an enthusiastic celebration of cyclic guanosine monophosphate (cGMP) and amply illustrates the importance of this field of science to patients and the way in which the field has evolved. It is exclusively devoted to this exciting and important signaling molecule, addressing all recent advances in understanding guanylate cyclase regulation, NO/sGC interactions, cGMP effector mechanisms and their pathophysiological and pharmacological implications. Particular attention will also be given to clinical applications of the novel cGMP-elevating drugs which are on the horizon, thus spanning the continuum from basic science to clinic.

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    Encyclopedia of Molecular Pharmacology, 2nd edition


    An essential text, this is a fully updated second edition of a classic, now in two volumes. It provides rapid access to information on molecular pharmacology for research scientists, clinicians and advanced students. With the A-Z format of over 2,000 entries, around 350 authors provide a complete reference to the area of molecular pharmacology. The book combines the knowledge of classic pharmacology with the more recent approach of the precise analysis of the molecular mechanisms by which drugs exert their effects. Short keyword entries define common acronyms, terms and phrases. In addition, detailed essays provide in-depth information on drugs, cellular processes, molecular targets, techniques, molecular mechanisms, and general principles.

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