Hypnotics and sedatives

Thursday, December 16, 2010



Hypnotics are drugs which produce sleep resembling natural sleep

Sedatives are drugs which reduce excitement without producing sleep
                                                                                                      
  1. Barbiturate derivatives
  2. Non – barbiturate derivatives
 
1 .Barbiturate derivatives

A. Long acting barbiturates   (8 -12 hours )

 Phenobarbitone
 Mephobarbitone
 Methylphenobarbitone
 Barbitone

B. Intermediate acting barbiturates

Amylobarbitone
Butobarbitone
Allobarbitone
Vinbarbitone

 C. Short acting barbiturates
 Pentobarbitone
Secobarbitone
Cyclobarbitone
Hepatobarbitone
  
D. Ultra short acting barbiturates
 Thiobarbitone
Hexabarbitone
Methobarbitone


2. Non –barbiturate derivatives


A. Benzodiazepines

Diazepam
Oxazepam

B. Chloral derivatives

Chloral hydrate
Chloral formamide
Butyl chloral hydrate

C. Aldehydes

Paraldehyde

D. Bromides

Potassium bromide
Sodium bromide
Ammonium bromide

E. Alcohols

Ethyl alcohol
Tribromoehamol
Amylene hydrate


F. Piperidine derivatives

Glutethimide
Methyprylon

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